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AQA GCSE Biology · Enzymes · 6 marks

Explain why the rate of reaction falls when the enzyme is heated above 50 °C.

Your answer

The enzyme denatures and the active site changes shape, so it stops working properly.

  • What's right —you named denaturing and the active site. That's 2 marks.

  • What went wrong —“stops working properly” is too vague. The scheme wants the effect on the substrate.

  • How to improve —write “the substrate can no longer bind to the active site”. That's both missing marks.

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Your question

6 marks
BiologyAQAEnzymes

Explain why the rate of reaction falls when the enzyme is heated above 50 °C.

Your answer

The enzyme denatures and the active site changes shape, so it stops working

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01

Notes

Biology · Enzymes

How enzymes work

Every enzyme has an active site shaped to fit one substrate. Heat it past 50 °C and that shape is lost — the reaction stops.

Substrate · active site

Exam tip

Write “changes shape”, never “the enzyme dies”.

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02

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Card 12 of 24

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What is the active site?

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03

Quiz

3 / 5 correct

Which factor can denature an enzyme?

  • ALow temperature
  • High temperature
  • CLow substrate concentration
  • DMore enzyme molecules

Correct. High temperatures change the shape of the active site.

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Biology · by topic

  • Enzymes86%
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