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Co-ordination & ResponseEdexcel GCSE Biology: Revision notes

Section 1

How does the brain control the body?

RegionFunction
Cerebral hemispheresMemory, personality, conscious thought, learning, intelligence, vision, voluntary movement
CerebellumBalance and coordination of muscle movement
Medulla oblongataUnconscious actions: heart rate, breathing
Key termscerebral hemispherescerebellummedulla oblongata
Common mistake

Do not confuse cerebellum (balance/coordination) with cerebrum (thought, voluntary movement).

Section 2

How do scientists investigate brain function?

CT scanning uses X-rays to show brain structure. PET scanning uses a radioactive tracer to show brain function/activity. Both avoid invasive surgery.

Key termsCT scanningPET scanning
Exam tip

CT = structure; PET = function.

Section 3

Why is treating the nervous system so difficult?

CNS neurones have very limited repair capacity. Spinal injuries can permanently block signals, causing paralysis. Brain tumours are hard to access due to the skull, and surgery risks damaging healthy tissue.

Key termsspinal injurybrain tumour

Section 4

How is information transmitted?

Pathway: sensory receptor → sensory neurone → relay neurone (CNS) → motor neurone → effector.

Axon carries impulses away from cell body; dendron carries impulses towards it; myelin sheath insulates the axon, speeding transmission.

Synapses: impulse triggers neurotransmitter release, which diffuses across the gap and binds receptors on the next neurone.

Key termssensory neuronerelay neuronemotor neuroneaxondendronmyelin sheathsynapseneurotransmitter
Think of it like this

Myelin sheath is like wire insulation — speeds up the signal.

Section 5

Reflex arc

Stimulus → receptor → sensory neurone → relay neurone → motor neurone → effector → response. Bypasses conscious brain processing for speed.

Key termsreflex arceffector
Example

Touching a hot object triggers withdrawal before pain is even registered by the brain.

Section 6

The eye

StructureFunction
CorneaRefracts light entering the eye
LensChanges shape to fine-tune focus
IrisControls pupil size/light entering
Rod cellsLow light, black/white
Cone cellsColour, fine detail, need bright light
Key termscornealensirisrod cellscone cells

Section 7

Eye defects and correction

DefectCauseCorrection
CataractsCloudy lensLens replacement surgery
Long-sightednessImage focuses behind retinaConvex lens
Short-sightednessImage focuses in front of retinaConcave lens
Colour blindnessFaulty cone cellsCannot be corrected
Key termscataractslong-sightednessshort-sightednesscolour blindness
Exam tip

Convex corrects long-sighted; concave corrects short-sighted.

Must Know

  • Cerebrum = thought/movement; cerebellum = balance; medulla = unconscious actions.
  • CT = structure; PET = function.
  • CNS damage hard to treat: limited repair, difficult access.
  • Impulse pathway with synapses using neurotransmitters.
  • Reflex arcs bypass conscious processing.
  • Cornea/lens focus light; rods = dim light; cones = colour.
  • Convex lens corrects long-sighted; concave corrects short-sighted.

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