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Circulatory SystemEdexcel GCSE Biology: Revision notes

Section 1

Structure of the Heart

Double pump: pulmonary circuit (lungs) and systemic circuit (body). Four chambers: two atria, two ventricles.

Key termsatriaventriclespulmonary circuitsystemic circuit

Section 2

Chamber Wall Thickness

Left ventricle thickest — pumps blood around whole body at high pressure. Right ventricle thinner — only pumps to nearby lungs.

Key termsleft ventricleright ventricle

Section 3

Valves

Atrioventricular valves (between atria/ventricles) and semilunar valves (at aorta/pulmonary artery base) prevent backflow.

Key termsatrioventricular valvessemilunar valves

Section 4

Major Blood Vessels

Aorta: left ventricle→body. Vena cava: body→right atrium. Pulmonary artery: carries deoxygenated blood (unusual). Pulmonary vein: carries oxygenated blood (unusual). Coronary arteries: supply heart muscle.

Key termsaortavena cavacoronary arteries

Section 5

Cardiac Output Calculations

Cardiac output = stroke volume × heart rate.

Key termsheart ratestroke volumecardiac output
Example

SV=70cm³, HR=72: CO=70×72=5040cm³/min.

Must Know

  • Heart: double pump, 4 chambers.
  • Left ventricle thicker (body pressure) vs right (lungs).
  • Valves prevent backflow.
  • Aorta=oxygenated out; vena cava=deoxygenated in; pulmonary artery/vein reversed.
  • Cardiac output = stroke volume × heart rate.

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