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InheritanceEdexcel IGCSE Biology: Flashcards

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What is the genome?

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What is the genome?
The entire DNA of an organism.
What is a gene?
A section of DNA that codes for a specific protein.
Describe the structure of DNA.
Two strands coiled to form a double helix, linked by paired bases: adenine with thymine, and cytosine with guanine.
How does RNA differ from DNA?
RNA is single-stranded and contains uracil instead of thymine.
What happens during transcription?
In the nucleus, the DNA base sequence of a gene is copied into a strand of mRNA.
What happens during translation?
At a ribosome, tRNA molecules bring amino acids matching the mRNA codons (via their anticodons), joining them to build a protein.
What is an allele?
An alternative form of a gene.
Define homozygous and heterozygous.
Homozygous = two identical alleles for a gene; heterozygous = two different alleles for a gene.
What is codominance?
When both alleles in a heterozygous individual are expressed in the phenotype, with neither masking the other.
What is polygenic inheritance?
Inheritance of a characteristic controlled by many genes acting together, producing continuous variation.
How is sex determined in humans?
By one pair of chromosomes: XX produces a female, XY produces a male; sperm carry either an X or Y chromosome, eggs always carry X.
What does mitosis produce, and when does it occur?
Two genetically identical daughter cells; occurs during growth, repair, cloning and asexual reproduction.
What does meiosis produce?
Four genetically different haploid gametes, each with half the chromosome number.
What are the diploid and haploid chromosome numbers in humans?
Diploid = 46 (in body cells), haploid = 23 (in gametes).
What is a mutation?
A rare, random change in genetic material that can be inherited.
What can increase the rate of mutation?
Exposure to ionising radiation and certain chemical mutagens.
Explain how antibiotic resistance spreads through a bacterial population.
A random mutation gives some bacteria resistance; when antibiotic is used, resistant bacteria survive and reproduce while non-resistant bacteria die, increasing the proportion of resistant bacteria.