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Amino acids and protein structureAQA A-Level Biology: Mind map

Amino acids
Peptide bond

Amino acids and proteins

From monomer to function

NH₂COOHR group
Four levels
Bonds
Function and test

Exam questions on Amino acids and protein structure

  1. Alanine is an amino acid whose R group is a methyl group, CH₃. Cysteine is an amino acid whose R group is CH₂SH, which contains sulfur.
    Explain why two cysteine molecules in a polypeptide can form a bond between their R groups that two alanine molecules cannot.2 marks
  2. Haemoglobin is a protein made from four polypeptide chains: two α chains of 141 amino acids each and two β chains of 146 amino acids each.
    Explain why a change in the sequence of amino acids in a protein can change its function.2 marks
  3. Ribonuclease is an enzyme made from a single polypeptide of 124 amino acids, folded into a compact three-dimensional shape. Its tertiary structure is held together by hydrogen bonds, ionic bonds and four disulfide bridges.
    Describe the primary, secondary and tertiary structure of ribonuclease.3 marks
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Written by the Exaim team, led by Shaun Daswani (Head of Upper Secondary, Improve ME Institute; MSc Financial Mathematics, Imperial College London; BSc, UCL) and Jason Daswani (operational lead, Improve ME Institute; LSE).