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The specific immune responseEdexcel A-Level Biology A: Flashcards

What these 14 flashcards ask

  • What is an antigen?
  • Describe the structure of an antibody.
  • What makes an antibody specific?
  • What is an antigen-presenting cell?
  • What do helper T cells do?
  • What do killer T cells do?
  • What are cytokines?
  • What is clonal selection?
  • What do plasma cells do?
  • What are memory cells?
  • Which response uses antibodies?
  • Why are killer T cells important against viruses?
  • How do antibodies help to destroy pathogens?
  • Where do T cells mature?

Exam questions on The specific immune response

  1. Antibodies are Y-shaped proteins made by plasma cells. Each antibody molecule is made of four polypeptide chains and has two identical antigen-binding sites. An antibody made against an influenza virus protein was tested and found to bind only to that influenza protein.
    Explain why this antibody does not bind to a protein on the surface of a measles virus.2 marks
  2. A patient is infected with a virus. Macrophages in the tissues engulf viral particles, and some days later killer T cells are found destroying virus-infected body cells.
    Describe the role of helper T cells in the immune response to this virus.2 marks
  3. Patient P has a rare inherited condition in which no B cells develop, although T cells are normal. Patient Q has a different condition in which helper T cells are absent, although B cells are normal. Both patients suffer repeated infections.
    Describe how a B cell is activated and produces antibodies against an antigen.3 marks
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Written by the Exaim team, led by Shaun Daswani (Head of Upper Secondary, Improve ME Institute; MSc Financial Mathematics, Imperial College London; BSc, UCL) and Jason Daswani (operational lead, Improve ME Institute; LSE).